Age of onset in successive generations of patients with a spondyloarthropathy.
نویسندگان
چکیده
منابع مشابه
Human Leukocyte Antigen B27 in 453 Asian Indian Patients with Seronegative Spondyloarthropathy
Background: Spondyloarthropathies are a group of closely related inflammatory arthritis which involve the axial skeleton and are negative for rheumatoid factor. Objective: This case-control study was conducted to examine HLA- B27 positivity in patients with seronegative spondyloarthritis (SSA) as per ESSG criteria and compare the frequency with healthy controls because a lower positivity is rep...
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Background: High prevalence of consanguineous marriages has been reported in Iran. Since this pattern of marriage may increase the prevalence of diseases with autosomal recessive pattern of expression, the study was assigned to determine this among patients referred to diabetes and osteoporosis clinics of Dr Shariati hospital, Tehran, Iran. Methods: The consanguineous marriage was studied amo...
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One of the most striking features in autosomal dominant polycystic kidney disease (ADPKD) is the difference at onset age of end-stage renal disease (ESRD). Modifier genes may play a role in this phenotypic variability. The mutated nitric oxide synthase 3 gene (NOS3), have a modifier effect on the severity of ADPKD by impairment of NOS3 activity and decreasing of renal vascular nitric oxide prod...
متن کاملFamilial aggregation of undifferentiated spondyloarthropathy associated with HLA-B7.
OBJECTIVE To report multiple cases of recurrent seronegative arthropathy, enthesopathy, or both, occurring in a single family in the absence of the HLA-B27 tissue type, coexistent psoriasis or inflammatory bowel disease. METHODS Three generations of one family together with their general practitioners completed a standard questionnaire. All subjects with a positive questionnaire and two rando...
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عنوان ژورنال:
- Annals of the rheumatic diseases
دوره 55 8 شماره
صفحات -
تاریخ انتشار 1996